Turkish Neurosurgery 2021 , Vol 31 , Num 4
Stereotactic Radiosurgery after Subtotal Resection of Critically-Located Grade I Meningioma: A Single-Center Experience and Review of Literature
Burak KARAASLAN1,Emrah CELTIKCI2,Erkut Baha BULDUK3,Alp Ozgun BORCEK2,Gokhan KURT2,Memduh KAYMAZ2,Sukru AYKOL2,Hakan EMMEZ2
1Cubuk Halil Sivgin State Hospital, Department of Neurosurgery, Ankara, Turkey
2Gazi University Faculty of Medicine, Department of Neurosurgery, Ankara, Turkey
3Atilim University Faculty of Medicine, Department of Neurosurgery, Ankara, Turkey
DOI : 10.5137/1019-5149.JTN.30181-20.2 AIM: To analyze the results of stereotactic radiosurgery in 295 patients with residual Grade I meningiomas located at parasellar region, petroclival region, cerebellopontine angle and parasagittal region.

MATERIAL and METHODS: A total of 295 patients with Grade 1 residual Meningiomas (197 women, 98 men), who were treated by adjuvant radiosurgery in Gazi University Gamma Knife Center between 2004-2015 were analyzed. WHO Grade 2 and 3 meningiomas were not included in our study. Minimum radiological follow-up was 24 months. The median follow-up was 54 months. The tumor volume, location, treatment dose, morbidity, progression free survival and tumor control rate were analyzed.

RESULTS: The median tumor volume was 5.2 cm3 (0.04-39.7), median age was 50 (20-80), median dose was 14 Gy and tumor control rate was 94.5% (stationary in 85.0%, volume reduction in 9.5%). Increase in tumor volume was seen in 16 patients (5.5%) and re-operation was performed in 5 of them (1.6%). Stereotactic radiosurgery was performed again for 8 patients (2.7%).The location of the tumors was as follows: 39.3% parasellar region, 20% cerebellopontine angle, 13.6% petroclival and 27.1% was parasagittal, falcine or convexity. Major morbidities were detected in 6 (2%) patients. Minor morbidities were detected in 18 (6.1%) patients.

CONCLUSION: Stereotactic radiosurgery is an effective and safe treatment modality for residual Grade I meningiomas. Keywords : Benign meningioma, Radiosurgery, Cavernous sinus, Petroclival, Cerebellopontine angle

Corresponding author : Burak KARAASLAN, burakkaraaslan08@hotmail.com