Turkish Neurosurgery 2013 , Vol 23 , Num 1
Primary Ewings Sarcoma of Cavernous Sinus in an Infant: A Case Report and Review of Literature
Mohana Rao PATIBANDLA1, Shantveer G UPPIN2, Amit Kumar THOTAKURA3, Manas K PANIGRAHI4, Sundaram CHALLA2
1Nizam's Institute of Medical Sciences, Department of Neurosurgery, Hyderabad, India
2Nizam's Institute of Medical Sciences, Department of Pathology, Hyderabad, India
3NRI Academy of Sciences, Department of Neurosurgery, Guntur, India
4Krishna Institute of Medical Sciences, Department of Neurosurgery, Hyderabad, India
DOI : 10.5137/1019-5149.JTN.4131-11.1 Ewing's / peripheral primitive neuroectodermal tumor (pPNET) of the cavernous sinus are extremely uncommon. We present clinical, radiological, pathological findings of Ewing's / pPNET involving the cavernous sinus in an eleven-month-old infant presenting with proptosis and 6th nerve palsy. MRI Contrast scans showed a well-defined, homogenously enhancing mass involving the right cavernous sinus location. Histopathology and immunohistochemical features were consistent with Ewing's/pPNET. The patient succumbed to disease in spite of starting chemotherapy. The clinical, radiological and pathological findings of previously reported cases of Ewing's sarcoma / pPNET involving the cavernous sinus are summarized. The histological differential diagnosis of primary intracranial Ewing's sarcoma / pPNET are discussed. Keywords : Ewing's sarcoma, Peripheral primitive neuroectodermal tumor, Cavernous sinus
Corresponding author : Panigrahi Manas Kumar, manaspanigrahi@live.com