Turkish Neurosurgery 2012 , Vol 22 , Num 4
Long-Term Benefit of Bilateral Subthalamic Deep Brain Stimulation on Camptocormia in Parkinson's Disease
Mark LYONS1, Orland BOUCHER1, Naresh PATEL1, Barry BIRCH1, Virgilio EVIDENTE2
1Mayo Clinic Arizona, Department of Neurological Surgery, Phoenix/AZ, USA
2Mayo Clinic Arizona, Department of Neurology, Phoenix/AZ, USA
DOI : 10.5137/1019-5149.JTN.3857-10.0 We report the case of a 63-year-old female with a long history of severe Parkinson's disease (PD) and subsequent onset of debilitating camptocormia who underwent successful bilateral subthalamic nucleus deep brain stimulation surgery (STN DBS). The literature and previous reports are reviewed. The patient history and details of the surgical procedure are reported including the implantable pulse generator (IPG) settings and response to stimulation. The results of her PD symptom and camptocormia improvements are discussed. Five year postoperatively, the patient has enjoyed good results for both her PD symptoms as well as significant and sustained improvement in her thoracolumbar flexion deformity. She remains on minimal medications and no longer requires any assistive devices for ambulation. Comparison and contrast of the current world literature on DBS for camptocormia is reviewed. We discuss the current targets used for DBS in the setting of camptocormia in the cases reported, both PD associated and not associated. The optimal target has yet to be defined and further work on appropriate patient selection is needed. Keywords : Camptocormia, Deep brain stimulation, Globus pallidus internus, Parkinson's disease, Subthalamic nucleus
Corresponding author : Mark Lyons, lyons.mark2@mayo.edu