Turkish Neurosurgery 2021 , Vol 31 , Num 5
Prevalence and Screening of Deep Vein Thrombosis in Patients with Osteoporotic Vertebral Fracture
Isamu MIURA1,Motoo KUBOTA1,Nobuhiko MOMOZAKI1,Takakazu KAWAMATA2,Masahito YUZURIHARA1
1Kameda Medical Center, Department of Spinal Surgery, Chiba, Japan
2Tokyo Women?s Medical University, Department of Neurosurgery, Tokyo, Japan
DOI : 10.5137/1019-5149.JTN.32962-20.2 AIM: To determine the prevalence of a deep vein thrombosis (DVT) in osteoporotic vertebral fractures.

MATERIAL and METHODS: Data were retrospectively collected from the medical records of 50 patients who were admitted to the Kameda Medical Center for osteoporotic vertebral fracture from 2019 to 2020. Inpatients were screened for DVT using D-dimer, and those who were screened positive underwent lower extremity venous ultrasonography to confirm DVT. Associations between various clinical factors and DVT were analyzed.

RESULTS: Six (12.0%) inpatients with osteoporotic vertebral fractures were found to have DVT. Two (33.3%) of the six had proximal DVT, although no pulmonary embolism was detected by chest computed tomography angiography. Univariate analysis showed that D-dimer values and duration from onset to hospitalization were predictive of DVT (p<0.05).

CONCLUSION: The prevalence of DVT among inpatients with osteoporotic vertebral fractures was 12.0%. This finding emphasizes the importance of DVT screening using D-dimer in those with osteoporotic vertebral fractures. Keywords : D-dimer, Deep vein thrombosis, Osteoporotic vertebral fracture, Screening, Thoracolumbar fracture

Corresponding author : Isamu MIURA, isamu2345@yahoo.co.jp